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10.1021/ja01200a520 135 DaughdrillG

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R.MylonasE.et al (2008)

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3.2.3 FUNDC1 mediated mitophagy The FUN14 domain-containing protein 1 (FUNDC1) is widely present on the mitochondrial outer membrane and acts as a regulator of mitochondrial autophagy in response to hypoxia, inducing Parkin-independent mitophagy (Liu et al., 2012)

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It opens a complex, nuanced discussion about synergy, safety, and the very mechanisms that make each compound compelling on its own

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If they are present, flick the barrel of the syringe gently until the bubbles rise to the top, then push them out carefully before withdrawing the needle

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